Acetylcholinesterase. Two types of modifications confer resistance to insecticide.
نویسندگان
چکیده
منابع مشابه
Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase.
Extensive utilization of pesticides against insects provides us with a good model for studying the adaptation of a eukaryotic genome to a strong selective pressure. One mechanism of resistance is the alteration of acetylcholinesterase (EC 3.1.1.7), the molecular target for organophosphates and carbamates. Here, we report the sequence analysis of the Ace gene in several resistant field strains o...
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متن کاملIdentification and characterization of mutations in housefly (Musca domestica) acetylcholinesterase involved in insecticide resistance.
Acetylcholinesterase (AChE) insensitive to organophosphate and carbamate insecticides has been identified as a major resistance mechanism in numerous arthropod species. However, the associated genetic changes have been reported in the AChE genes from only three insect species; their role in conferring insecticide insensitivity has been confirmed, using functional expression, only for those in D...
متن کاملIndependent duplications of the acetylcholinesterase gene conferring insecticide resistance in the mosquito Culex pipiens.
Gene duplication is thought to be the main potential source of material for the evolution of new gene functions. Several models have been proposed for the evolution of new functions through duplication, most based on ancient events (Myr). We provide molecular evidence for the occurrence of several (at least 3) independent duplications of the ace-1 locus in the mosquito Culex pipiens, selected i...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1992
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)49708-1